Resident Research Platform

  Comparative Medicine

Adenovirus-mediated Gene Transfer in Rat Tenocytes for Nonsurgical Treatment of Tendon Injuries-Tendon injuries are prevalent in human and veterinary medicine, yet few non-surgical treatments exist. While oral anti-inflammatory medications and intra-articular injections provide temporary relief, they do not repair the damaged tissue. Therefore, alternatives that strengthen tendons could improve clinical outcomes. Gene therapy has a potential role in strengthening tendons and preventing degenerative tearing. Tenocytes are the most abundant cells in tendons. Proof-of-concept experiments in tenocytes with the expression of marker genes, e.g. GFP (green fluorescent protein), are the first step toward gene therapy for tendon injuries.; A Rare Case of Pyometra in a Cynomologus Macaque (Macaca fascicularis)-This case highlights an important risk for endometriosis treatment with progestin in macaques; Bathe Your Pigs! Dermatitis in a Swine Model of Nonalcoholic Steatohepatitis-While rodent models of nonalcoholic steatohepatitis (NASH) are well-established, swine models of NASH offer an exciting opportunity to more closely mimic disease in humans. With this unique model comes unique challenges. This session covers the unexpected development of dermatitis in pigs fed a NASH-inducing diet with an emphasis on lesion development and the clinical care necessary to manage these animals. Leuocytozoonosis in an Adult Male Bourbon Red Turkey-Leucocytozoon spp. are hemoparasites of birds that usually cause subclinical infections but may cause fatal disease. This session will discuss the history, clinical signs, and pathological findings of a research turkey with fatal leucocytozoonosis.